Abstract Tropical reef fishes exhibit a large disparity of organismal morphologies contributing to their astonishing biodiversity.Morphological disparity, scaling from differences among individuals within populations to differences among species, is governed by ecological and evolutionary processes.Here, we examined the relationship between intra-
Single-Target Regulators Constitute the Minority Group of Transcription Factors in Escherichia coli K-12
The identification of regulatory targets of all transcription factors (TFs) is critical for read more understanding the entire network of genome regulation.A total of approximately 300 TFs exist in the model prokaryote Escherichia coli K-12, but the identification of whole sets of their direct targets is impossible with use of in vivo approaches.Fo
Politics is local: State legislator voting on restrictive voter identification legislation
The marked increase in restrictive voter identification (ID) laws since the 2010 elections reveals the extreme partisan polarization in those state legislatures advancing this reform.Unlike previous studies that examine state-level factors expected to influence passage of restrictive voter ID bills, this study is the first to investigate the questi
Imagens em materiais didáticos impressos para o ensino de Física num curso de Licenciatura semipresencial
O objetivo do presente artigo é expor o resultado da replica beach walk candle análise das imagens presentes em material didático impresso utilizado na disciplina Introdução às Ciências Físicas 1 (ICF 1) da modalidade semipresencial do curso de Licenciatura em Física da Universidade Federal do Rio de Janeiro (UFRJ).Para isso, examinamos as
Gag mutations strongly contribute to HIV-1 resistance to protease inhibitors in highly drug-experienced patients besides compensating for fitness loss.
Human immunodeficiency virus type 1 (HIV-1) resistance to protease inhibitors (PI) results from mutations in the viral protease (PR) that gotrax handlebar reduce PI binding but also decrease viral replicative capacity (RC).Additional mutations compensating for the RC loss subsequently accumulate within PR and in Gag substrate cleavage sites.We exam